The JC Virus BIO-PROBE labeled probe is prepared by nick translation of a clone of the entire JC virus genome. JC virus, a member of the papovavirus family, usually causes subclinical infections. However, in immunocompromised individuals it can cause a fatal demyelinating brain disease, progressive multifocal leukoencephalopathy. JC virus is also neurooncogenic in primates. Fragment size range: 100-1000 base pairs (as estimated by agarose gel electrophoresis). Concentration: 20µg/ml. Formulation: Liquid. In 10mM TRIS HCl, pH 7.5, containing 1mM EDTA. Long Term Storage: -20°C.